Impact of glucose dosing regimens on modeling of glucose tolerance and β -cell function by intravenous glucose tolerance test in diet-induced obese mice

Impact of glucose dosing regimens on modeling of glucose tolerance and β‐cell function by intravenous glucose tolerance test in diet‐induced obese mice

Insulin sensitivity declines in overweight and obese individuals and, under normal conditions, insulin secretion adaptively increases which in healthy non-diabetic subjects maintains normal glycemia. This adaptation is best described by the disposition index derived from modeling of insulin and glucose data from an intravenous glucose tolerance testing (IVGTT). One caveat of the IVGTT is that b...

Intravenous Glucose Tolerance Test and Glucose Kinetic Parameters in Rabbits

The purpose of this study was to determine the normal range and test variability for intravenous glucose tolerance test (IVGTT) in rabbits. Fifty one clinically healthy New Zealand white rabbits of both sexes (31 female and 20 male), 3.5−4 months of age and weighing 2.8 to 3.7 kg were used. The IVGTT was performed after an overnight fasting period of 12 h by intravenous injection of 40% glucose...

Effect of Intravenous Glucose Tolerance Test on Bone Turnover Markers in Adults with Normal Glucose Tolerance

BACKGROUND It is well known that enteral nutrients result in acute suppression of bone turnover markers (BTMs), and incretin hormones are believed to play a significant role in this physiological skeletal response. However, there is limited research exploring the impact of parenteral nutrients on BTMs. Our aim was to assess the influence of intravenous glucose on BTMs in adults with normal gluc...

Intravenous Glucose Tolerance Test in Normal Persons

as a supplement to the oral method has been pointed out by many workers. Moreover, the possibility of error in the result of oral method due to diminished absorption has been shown by Beeler, Bryan, Cathcart and Fitz (1922). The flat blood sugar curve obtained by Thaysen (1929) after the oral administration of glucose, as has been shown by the author, is due to the diminished absorption of gluc...

A standard intravenous glucose tolerance test.